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Article

Clinical and bacterial determinants of unfavorable tuberculosis treatment outcomes: an observational study in Georgia.

Genome medicine - 14 Nov 2025

Goig Galo A, Loiseau Chloé, Maghradze Nino, Mchedlishvili Kakha, Avaliani Teona, Tsutsunava Ana, Brites Daniela, Kalkan Sevda, Borrell Sonia, Aspindzelashvili Rusudan, Avaliani Zaza, Kipiani Maia, Tukvadze Nestani, Jugheli Levan, Gagneux Sebastien

Abstract excerpt

BACKGROUND: Tuberculosis (TB) remains a major public health concern. Improving TB control programs and treatment success requires a deeper understanding of the factors that determine disease presentation and treatment outcomes. While the importance of patient factors is well established, our understanding of the bacterial determinants of disease presentation and treatment outcomes in TB remains limited. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41239519
DOI: 10.1186/s13073-025-01555-0
PMCID: PMC12619330

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