Article

Within-host pathogen population diversity predicts treatment response in Tuberculosis

2026-06-19

Abstract excerpt

<h4>Background</h4> Tuberculosis (TB) treatment outcomes remain suboptimal, and standard clinical diagnostics cannot reliably identify patients at high risk of treatment failure or relapse at the time of diagnosis. While within-host Mycobacterium tuberculosis genetic diversity is hypothesized to reflect the viable bacterial burden and adaptive capacity of the infection, its clinical prognostic value remains unkn...

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Literature Corpus work: 850356c1-d894-5d09-a2ec-b12422b140f1
DOI: 10.64898/2026.06.16.26355818

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