Back to search

Article

Batch effects and the effective design of single-cell gene expression studies

2016-07-08

Abstract excerpt

Single cell RNA sequencing (scRNA-seq) can be used to characterize variation in gene expression levels at high resolution. However, the sources of experimental noise in scRNA-seq are not yet well understood. We investigated the technical variation associated with sample processing using the single cell Fluidigm C1 platform. To do so, we processed three C1 replicates from three human induced pluripotent stem cell (...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
85ab0132-61bf-5363-9786-5dac768e05e0
DOI
10.1101/062919
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Batch effects and the effective design of single-cell gene expression studiesDOI 10.1101/062919
Select a neighboring publication to make it the new centre.