Article

scImpute: Accurate And Robust Imputation For Single Cell RNA-Seq Data

2017-05-24

Abstract excerpt

The emerging single cell RNA sequencing (scRNA-seq) technologies enable the investigation of transcriptomic landscapes at single-cell resolution. The analysis of scRNA-seq data is complicated by excess zero or near zero counts, the so-called dropouts due to the low amounts of mRNA sequenced within individual cells. Downstream analysis of scRNA-seq would be severely biased if the dropout events are not properly cor...

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Literature Corpus work: ab52e61b-1614-5bbb-97d9-f8b30440ea81
DOI: 10.1101/141598

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