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Article

Allele-specific single-cell RNA sequencing reveals different architectures of intrinsic and extrinsic gene expression noises.

Nucleic acids research - 24 Jan 2020

Sun Mengyi, Zhang Jianzhi

Abstract excerpt

Gene expression noise refers to the variation of the expression level of a gene among isogenic cells in the same environment, and has two sources: extrinsic noise arising from the disparity of the cell state and intrinsic noise arising from the stochastic process of gene expression in the same cell state. Due to the low throughput of the existing method for measuring the two noise components, the architectures of...

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Identifiers

PMID: 31799601
DOI: 10.1093/nar/gkz1134
PMCID: PMC6954418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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