Article
Evaluation of tools for highly variable gene discovery from single-cell RNA-seq data.
Briefings in bioinformatics - 19 Jul 2019
Yip Shun H, Sham Pak Chung, Wang Junwen
Abstract excerpt
Traditional RNA sequencing (RNA-seq) allows the detection of gene expression variations between two or more cell populations through differentially expressed gene (DEG) analysis. However, genes that contribute to cell-to-cell differences are not discoverable with RNA-seq because RNA-seq samples are obtained from a mixture of cells. Single-cell RNA-seq (scRNA-seq) allows the detection of gene expression in each...
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