Article

Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug response

2024-07-16

Abstract excerpt

<title>Abstract</title> <p>Breast cancer (BCa) is a major global health challenge, characterized by chromosomal instability (CIN) and subsequent acquisition of extensive somatic copy number alterations (CNAs). CNAs including amplifications and deletions, significantly influence intra-tumor heterogeneity and the tumor microenvironment (TME). Among these, the loss of chromosome 13q14.2 emerges as a considerable fac...

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Literature Corpus work: 8574adc6-c3f1-5b7a-949e-fa20ecc3e8d5
DOI: 10.21203/rs.3.rs-4594599/v1

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