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A new insight into the impact of copy number variations on cell cycle deregulation of luminal-type breast cancer

12 Feb 2025

Abstract excerpt

(Luminal subtype), representing over 70% of breast tumors, is a genetically diverse group. Structural and Numerical-Chromosomal instability initiates tumor development and is recognized as the primary driver of genetic alteration in luminal breast tumors. Genomic instability refers to the increased tendency of cancer cells to accumulate genomic alterations during cell proliferation. The cell cycle check-point...

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PMID: 40017494
DOI: 10.3389/or.2025.1516409

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