Article

Cell-autonomous Wnt activity promotes transient re-programming and cell cycle re-entry of coronary artery endothelial cells

2026-02-23

Abstract excerpt

Coronary occlusion leads to formation of collateral arteries connecting occluded and perfused arteries. This process, namely artery reassembly, is temporally restricted to the cardiac regenerative window in mice and relies on cell cycle re-entry of post-mitotic artery endothelial cells (ECs). Analyses of single cell RNA sequencing data of ischemic mouse hearts led to identification of Wnt activity in proliferating...

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Literature Corpus work: 856c15d7-0bea-58d8-bcc1-f55365066642
DOI: 10.64898/2026.02.23.707374

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