Article

Development of Pial Collaterals by Extension of Pre-existing Artery Tips

2023-12-08

Abstract excerpt

<h4>SUMMARY</h4> Pial collaterals provide protection from ischemic damage and improve prognosis of stroke patients. The origin or precise sequence of events underlying pial collateral development is unclear and has prevented clinicians from adapting new vascularization and regeneration therapies. We use genetic lineage tracing and intra-vital imaging of mouse brains at cellular resolution to show that during embr...

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Literature Corpus work: 70667bd9-0dfc-536a-a42e-7c10d55179a3
DOI: 10.1101/2023.12.07.570539

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