Article

A Perturb-seq screen guided by species divergence uncovers pathways for collateral artery formation

2026-05-04

Abstract excerpt

Collateral arteries are natural bypasses that can reroute blood flow around arterial blockages, limiting tissue injury during stroke and coronary artery disease. Despite their clinical effectiveness, therapeutic strategies to stimulate collateral artery growth remain unavailable due to our limited understanding of their developmental mechanisms. Remarkably, guinea pigs display exceptionally dense collateral artery...

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Identifiers and source

Literature Corpus work: 71987289-ce58-5741-9226-3295d2c7e43b
DOI: 10.64898/2026.04.29.721711

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