Article

Remdesivir induced viral RNA and subgenomic RNA suppression, and evolution of viral variants in SARS-CoV-2 infected patients

2020-11-20

Abstract excerpt

While changes in SARS-CoV-2 viral load over time have been documented, detailed information on the impact of remdesivir and how it might alter intra-host viral evolution is limited. Sequential viral loads and deep sequencing of SARS-CoV-2 recovered from the upper respiratory tract of hospitalised children revealed that remdesivir treatment suppressed viral RNA levels in one patient but not in a second infected wit...

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Literature Corpus work: 8528e0e9-a39f-5b86-9ca8-29c23332f273
DOI: 10.1101/2020.11.18.20230599

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