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Article

Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection

16 Aug 2022

Abstract excerpt

We here investigate the impact of antiviral treatments such as remdesivir on intra-host genomic diversity and emergence of SARS-CoV2 variants in patients with a prolonged course of infection. Sequencing and variant analysis performed in 112 longitudinal respiratory samples from 14 SARS-CoV2-infected patients with severe disease progression show that major frequency variants do not generally arise during prolonged...

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PMID: 36075217
DOI: 10.1016/j.xcrm.2022.100735

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