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Use of whole genome sequencing to identify low-frequency mutations in COVID-19 patients treated with remdesivir

2022-11-22

Abstract excerpt

<h4>Background</h4> We investigate the effects of remdesivir (RDV) treatment on intra-host SARS-CoV-2 diversity and low-frequency mutations in moderately ill hospitalized COVID-19 patients and compare them to patients without RDV treatment. <h4>Methods</h4> Sequential collections of nasopharyngeal and mid-turbinate swabs were obtained from 16 patients with and 31 patients without RDV treatment. A total of 113 samp...

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Literature Corpus work
5ec8e499-b9e3-5645-a067-e0d1aac8ad81
DOI
10.1101/2022.11.20.22282552
Open publication

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Use of whole genome sequencing to identify low-frequency mutations in COVID-19 patients treated with remdesivirDOI 10.1101/2022.11.20.22282552
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