Article
Diversity and disease pathogenesis in Mycobacterium tuberculosis.
Trends in microbiology - 1 Jan 2015
Warner Digby F, Koch Anastasia, Mizrahi Valerie
Abstract excerpt
The increasing availability of whole-genome sequence (WGS) data for Mycobacterium tuberculosis, the bacterium that causes tuberculosis (TB), suggests that circulating genotypes have been molded by three dominant evolutionary forces: long-term persistence within the human population, which requires a core programme of infection, disease, and transmission; selective pressure on specific genomic loci, which provides...
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