Article

Dynamics of within-host<i>Mycobacterium tuberculosis</i>diversity and heteroresistance during treatment

2020-02-04

Abstract excerpt

<h4>Background</h4> Studying within-host genetic diversity of Mycobacterium tuberculosis ( Mtb ) in patients during treatment may identify adaptations to antibiotic and immune pressure. Understanding the significance of genetic heteroresistance, and more specifically heterozygous resistance-associated variants (RAVs), is clinically important given increasing use of rapid molecular tests and whole genome sequencing...

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Literature Corpus work: cfea931b-d277-5d80-a8fc-ee1e9a0e1d87
DOI: 10.1101/2020.02.03.20019786

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