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Article

The role of TARBP2 in the development and progression of cancers.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2016

Yu Xin, Li Zheng

Abstract excerpt

TARBP2 is a RNA-binding protein (RBP) involved in miRNA processing and maturation. TARBP2 plays significant roles in many biological and pathological conditions, including viral expression of HIV-1, microsatellite instability, cancer stem cell properties, and tumor progression. Overexpression of TARBP2 was observed in many cancers such as prostate cancer, cutaneous malignant melanoma, and adrenocortical...

Topics

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Disease Progression
Down-Regulation
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
MicroRNAs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Instability

Neoplastic Stem Cells

RNA-Binding Proteins

Source

Identifiers

PMID: 26486325
DOI: 10.1007/s13277-015-4273-6

Genes

TARBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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