Article

Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches

2023-11-10

Abstract excerpt

Controlling the time and place of nephron formation in vitro would improve nephron density and connectivity in next-generation kidney replacement tissues. Recent developments in kidney organoid technology have paved the way to achieving self-sustaining nephrogenic niches in vitro . The physical and geometric structure of the niche are key control parameters in tissue engineering approaches. However, their relati...

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Literature Corpus work: 84f37a48-a546-5ccc-aaa5-c911b5b8139b
DOI: 10.1101/2023.11.08.566308

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