Article
Forming nephrons promote nephron progenitor maintenance and branching morphogenesis via paracrine BMP4 signalling under the control of <i>Wnt4</i>
2023-11-19
Abstract excerpt
Kidney development is known to be driven by interactions between stromal, nephron and ureteric epithelium progenitors in the nephrogenic niche. In contrast, the epithelial nephrons generated in this environment have largely been considered a product of niche rather than an active participant in the signalling interactions that maintain it. However, knockout of Wnt4 , a gene required for nephron formation and stro...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- e2f93f35-f549-5750-a122-59dbb4ad992d
- DOI
- 10.1101/2023.11.19.567482