Article

Effect of CSF1R Inhibitor on Glial Cells Population and Remyelination in The Cuprizone Model

2021-02-08

Abstract excerpt

<title>Abstract</title> <p>Multiple sclerosis is a kind of autoimmune and demyelinating disease and its pathological symptoms include inflammation, myelin loss, astrocytosis, and microgliosis. The colony stimulating factor 1 receptor (CSF1R), as an essential factor for the microglial function, and PLX3397 is its specific inhibitor. In this study, we assessed the effect of different doses of PLX3397 for microglial...

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Literature Corpus work: 849a812b-2596-5917-81a2-226e77174b4e
DOI: 10.21203/rs.3.rs-159459/v1

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