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Targeted Modulation of Inflammatory Lymphocytes and Neurogenesis/Neuroprotection Associated Genes by Curcumin and a Novel Derivative of Curcumin on Mice Experimental Autoimmune Encephalomyelitis Model

2022-06-21

Abstract excerpt

<title>Abstract</title> <p>Multiple sclerosis (MS) is a chronic demyelinating disease that causes neurological disabilities mostly in young adults. Curcumin (CUR), a polyphenol found in Turmeric, has anti-inflammatory and neuroprotective properties in autoimmune diseases including MS, although it has low bioavailability and solubility. In the present study, administration of CUR and FCUR, a potent synthetic deriv...

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Literature Corpus work
0ed296d0-244e-55c8-a82d-4ef46825f2fa
DOI
10.21203/rs.3.rs-1717133/v1
Open publication

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