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Human cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p inactivation of FOXO3a protects CD34 <sup>+</sup> hematopoietic progenitor cells from apoptosis

2020-09-29

Abstract excerpt

Human cytomegalovirus (HCMV) infection of myeloid-lineage cells, such as CD34 + hematopoietic progenitor cells (HPCs) or monocytes results in the upregulation of anti-apoptotic cellular proteins that protect the newly infected cells from programmed cell death. The mechanisms used by HCMV to regulate pro-apoptotic cellular proteins upon infection of CD34 + HPCs has not been fully explored. Here we show that HCMV...

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Literature Corpus work
84903a49-ccc6-5854-9323-2d5a31bd6b44
DOI
10.1101/2020.09.28.317859
Open publication

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Human cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p inactivation of FOXO3a protects CD34 <sup>+</sup> hematopoietic progenitor cells from apoptosisDOI 10.1101/2020.09.28.317859
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