Article

VIP-OT: Dissecting Single-Cell Biochemical State Dynamics under Perturbation via Vibrational Painting and Optimal Transport

2025-12-12

Abstract excerpt

Dissecting the heterogeneous response of individual cells towards genetic and chemical perturbations is central to understanding the dynamic functions of cells and multicellular systems. However, characterizing and modeling how individual cells transition between different states remains a major challenge. Vibrational imaging provides high-content, biochemically informative, label-free molecular fingerprints of si...

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Literature Corpus work: 848590f9-9a32-53c1-94a7-9ca10f838c4a
DOI: 10.64898/2025.12.09.693255

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