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Systematic alteration of in vitro metabolic environments reveals empirical growth relationships in cancer cell phenotypes.

Cell reports - 19 Jan 2021

Kochanowski Karl, Sander Timur, Link Hannes, Chang Jeremy, Altschuler Steven J, Wu Lani F

Abstract excerpt

Cancer cells, like microbes, live in complex metabolic environments. Recent evidence suggests that microbial behavior across metabolic environments is well described by simple empirical growth relationships, or growth laws. Do such empirical growth relationships also exist in cancer cells? To test this question, we develop a high-throughput approach to extract quantitative measurements of cancer cell behaviors in...

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Identifiers

PMID: 33472066
DOI: 10.1016/j.celrep.2020.108647
PMCID: PMC7877896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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