Article

Reading canonical and modified nucleotides in 16S ribosomal RNA using nanopore direct RNA sequencing

2017-04-29

Abstract excerpt

The ribosome small subunit is expressed in all living cells. It performs numerous essential functions during translation, including formation of the initiation complex and proofreading of base-pairs between mRNA codons and tRNA anticodons. The core constituent of the small ribosomal subunit is a ∼1.5 kb RNA strand in prokaryotes (16S rRNA) and a homologous ∼1.8 kb RNA strand in eukaryotes (18S rRNA). Traditional s...

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Identifiers and source

Literature Corpus work: 847a8821-0ff0-539b-93a4-cccb096e5911
DOI: 10.1101/132274

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