Article
New Twists in Detecting mRNA Modification Dynamics.
Trends in biotechnology - 1 Jan 2021
Anreiter Ina, Mir Quoseena, Simpson Jared T, Janga Sarath C, Soller Matthias
Abstract excerpt
Modified nucleotides in mRNA are an essential addition to the standard genetic code of four nucleotides in animals, plants, and their viruses. The emerging field of epitranscriptomics examines nucleotide modifications in mRNA and their impact on gene expression. The low abundance of nucleotide modifications and technical limitations, however, have hampered systematic analysis of their occurrence and functions....
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