Article

Decoding bacterial methylomes in four public health-relevant microbial species: Nanopore sequencing enables reproducible analysis of DNA modifications

2025-02-02

Abstract excerpt

Investigating bacterial methylation profiles provides essential complementary information to the native DNA sequence, significantly extending our understanding of how DNA modifications influence virulence, antibiotic resistance, and the ability of bacteria to evade the immune system. Recent advancements in real-time Nanopore sequencing and basecalling algorithms have enabled the direct detection of modified bases...

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Literature Corpus work: 13ba3418-6030-5b6d-996e-ed3e909b146a
DOI: 10.1101/2025.01.29.635492

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