Article

Single cell functional immunogenomics of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention

2025-07-04

Abstract excerpt

<h4>ABSTRACT</h4> The fallopian tube (FT) is increasingly recognized as the site of origin for high-grade serous ovarian cancer (HGSOC), yet its immune landscape and potential role in tumor surveillance remain poorly understood. Here, we employ single-cell RNA sequencing (scRNA-seq) and paired single-cell T-cell receptor sequencing (scTCR-seq) to profile tissue-resident memory-like T cells (TRMLs) from matched no...

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Literature Corpus work: 844103c4-bd55-53f2-a9cd-c2f441610047
DOI: 10.1101/2025.06.30.662408

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