Article

Unraveling Tumor-Immune Heterogeneity in Advanced Ovarian Cancer Uncovers Immunogenic Effect of Chemotherapy

2018-10-12

Abstract excerpt

<h4>ABSTRACT</h4> In metastatic cancer, the role of heterogeneity at the tumor-immune microenvironment, its molecular underpinnings and clinical relevance remain largely unexplored. To understand tumor-immune dynamics at baseline and upon chemotherapy treatment, we performed unbiased pathway and cell type-specific immunogenomics analysis of treatment-naive (38 samples from 8 patients) and paired chemotherapy trea...

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Literature Corpus work: 48e23ccf-f252-5cb8-8820-342aa0d95b0a
DOI: 10.1101/441428

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