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Article

Pervasive chromatin remodeling at X-inactivation escape genes in schizophrenic males

2018-04-13

Abstract excerpt

Reanalyzing a large methylome dataset of 225 schizophrenic and 450 control samples derived from the prefrontal cortex revealed that 6 male patients have predominantly hypomethylated probes mostly on chromosome X, affecting the same genes in all six. Network analysis of the differentially methylated genes revealed a dense network of transcription factors, histone and chromatin remodeling proteins, with 15 of the X-...

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Literature Corpus work
843774af-30d7-5802-9fad-c7d4937028df
DOI
10.1101/300624
Open publication

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Pervasive chromatin remodeling at X-inactivation escape genes in schizophrenic malesDOI 10.1101/300624
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