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Article

Single molecule in situ hybridization reveals distinct localizations of schizophrenia risk-related transcripts SNX19 and AS3MT in human brain.

Molecular psychiatry - 1 Jul 2021

Takahashi Yoichiro, Maynard Kristen R, Tippani Madhavi, Jaffe Andrew E, Martinowich Keri, Kleinman Joel E, Weinberger Daniel R, Hyde Thomas M

Abstract excerpt

Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with schizophrenia risk. Integration of RNA-sequencing data from postmortem human brains with these risk SNPs identified transcripts associated with increased schizophrenia susceptibility, including a class of exon 9-spliced isoforms of Sorting nexin-19 (SNX19d9) and an isoform of Arsenic methyltransferase (AS3MT)...

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Identifiers

PMID: 33649454
DOI: 10.1038/s41380-021-01046-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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