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Article

SARS-CoV-2 specific plasma cells acquire long-lived phenotypes in human bone marrow.

EBioMedicine - 1 Sept 2023

Schulz Axel R, Fiebig Leonard, Hirseland Heike, Diekmann Lisa-Marie, Reinke Simon, Hardt Sebastian, Niedobitek Antonia, Mei Henrik E

Abstract excerpt

BACKGROUND: SARS-CoV-2 specific antibody-secreting plasma cells (PC) mediating specific humoral immunity have been identified in the human bone marrow (BM) after COVID-19 or vaccination against SARS-CoV-2. However, it remained unclear whether or not they acquire phenotypes of human memory plasma cells. METHODS: SARS-CoV-2-specific human bone marrow plasma cells (BMPC) were characterised by tetramer-based,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37556944
DOI: 10.1016/j.ebiom.2023.104735
PMCID: PMC10432952

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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