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The Majority of SARS-CoV-2 Plasma Cells are Excluded from the Bone Marrow Long-Lived Compartment 33 Months after mRNA Vaccination

2024-03-13

Abstract excerpt

<title>Abstract</title> <p>The goal of any vaccine is to induce long-lived plasma cells (LLPC) to provide life-long protection. Natural infection by influenza, measles, or mumps viruses generates bone marrow (BM) LLPC similar to tetanus vaccination which affords safeguards for decades. Although the SARS-CoV-2 mRNA vaccines protect from severe disease, the serologic half-life is short-lived even though SARS-CoV-2-...

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Literature Corpus work: 0d0c2a12-b836-5449-92ed-c723abc46bbd
DOI: 10.21203/rs.3.rs-3979237/v1

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