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SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination

27 Sept 2024

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines are effective at protecting from severe disease, but the protective antibodies wane rapidly even though SARS-CoV-2-specific plasma cells can be found in the bone marrow (BM). Here, to explore this paradox, we enrolled 19 healthy adults at 2.5-33 months after receipt of a SARS-CoV-2 mRNA vaccine and measured influenza-, tetanus- or...

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PMID: 39333316
DOI: 10.1038/s41591-024-03278-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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