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Telmisartan-Induced Alteration of Voltage-Gated Na<sup>+</sup> Currents: Integrated Experimental and In Silico Approaches

2026-03-06

Abstract excerpt

Telmisartan (TEL) is a non-peptide, orally administered antihypertensive agent primarily known as angiotensin II type 1 (AT1) blocker. In this review, we provide a detailed overview of how TEL modulates voltage-gated Na+ current (INa) and affects action potential (AP) firing behavior. TEL exerts differential stimulatory effects on the peak and late components of INa when subjected to brief depolarizing pulses acro...

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Literature Corpus work
83515020-dba0-5bef-b00b-e2ae2428e599
DOI
10.20944/preprints202603.0533.v1
Open publication

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Telmisartan-Induced Alteration of Voltage-Gated Na<sup>+</sup> Currents: Integrated Experimental and In Silico ApproachesDOI 10.20944/preprints202603.0533.v1
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