Modifications of sodium channel voltage dependence induce arrhythmia-favouring dynamics of cardiac action potentials.

Abstract excerpt

Heart arrhythmia is a pathological condition where the sequence of electrical impulses in the heart deviates from the normal rhythm. It is often associated with specific channelopathies in cardiac tissue, yet how precisely the changes in ionic channels affect the electrical activity of cardiac cells is still an open question. Even though sodium channel mutations that underlie cardiac syndromes like the Long-Q-T...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Action Potentials
• Share to Arrhythmias, Cardiac
• Share to Brugada Syndrome