Article

Long-Term Inactivation of Sodium Channels as a Mechanism of Adaptation in CA1 Pyramidal Neurons

2021-10-28

Abstract excerpt

Many hippocampal CA1 pyramidal cells function as place cells, increasing their firing rate when a specific place field is traversed. The dependence of CA1 place cell firing on position within the place field is asymmetric. We investigated the source of this asymmetry by injecting triangular depolarizing current ramps to approximate the spatially-tuned, temporally-diffuse depolarizing synaptic input received by the...

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Literature Corpus work: 309cea7f-b550-5806-b65d-3baf40b21f5e
DOI: 10.1101/2021.10.26.465936

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