Article
Molecular determinants for α-tubulin methylation by SETD2
2020-10-21
Abstract excerpt
Post-translational modifications to tubulin are important for many microtubule-based functions inside cells. A recently identified tubulin modification, methylation, occurs on mitotic spindle microtubules during cell division, and is enzymatically added to tubulin by the histone methyltransferase SETD2. We used a truncated version of human SETD2 (tSETD2) containing the catalytic SET and C-terminal Set2 Rpb1 intera...
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Identifiers and source
- Literature Corpus work
- 83015314-4029-5eee-8279-418697dc90c9
- DOI
- 10.1101/2020.10.21.349365