Article
The tubulin database: Linking mutations, modifications, ligands and local interactions.
PloS one - 1 Jan 2023
Abbaali Izra, Truong Danny, Day Shania Deon, Mushayeed Faliha, Ganesh Bhargavi, Haro-Ramirez Nancy, Isles Juliet, Nag Hindol, Pham Catherine, Shah Priya, Tomar Ishaan, Manel-Romero Carolina, Morrissette Naomi S
Abstract excerpt
Microtubules are polymeric filaments, constructed of α-β tubulin heterodimers that underlie critical subcellular structures in eukaryotic organisms. Four homologous proteins (γ-, δ-, ε- and ζ-tubulin) additionally contribute to specialized microtubule functions. Although there is an immense volume of publicly available data pertaining to tubulins, it is difficult to assimilate all potentially relevant information...
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