Article

Inhibition of HVEM suppresses growth and invasion of mesenchymal glioblastoma

2026-01-17

Abstract excerpt

Mesenchymal glioblastoma is a subtype of glioblastoma multiforme (GBM) characterized by pronounced inflammatory features and resistance to conventional therapies. Proneural GBM acquires a mesenchymal phenotype through proneural-mesenchymal transition (PMT), in which NF-κB signaling plays a central role. Through RNA-sequencing analysis of glioma-initiating cells (GICs), we found that expression of herpes virus entr...

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Literature Corpus work: 830025f9-6f48-5c2a-b252-a93b58f80d1d
DOI: 10.64898/2026.01.16.699674

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