Article

Loss of ELAVL2 is associated with aggressive mesenchymal transition in glioblastoma

2023-06-02

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM), the most lethal type of primary brain cancer, is characterized by cellular and molecular plasticity, which leads to intratumoral heterogeneity and hinders effective treatment. However, the regulation of such plasticity, including mesenchymal (MES) transition, is poorly understood. Here, we demonstrate that the RNA-binding protein ELAVL2 regulates aggressive MES trans...

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Literature Corpus work: d3ee11b8-bc9d-5433-9874-b4609f16d252
DOI: 10.21203/rs.3.rs-2940854/v1

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