Article

Progressive domain segregation in early embryonic development and underlying correlation to genetic and epigenetic changes

2019-01-17

Abstract excerpt

<h4>ABSTRACT</h4> Chromatin undergoes drastic structural organization and epigenetic reprogramming during embryonic development. We present here a consistent view of the chromatin structural change, epigenetic reprogramming and the corresponding sequence dependence in both mouse and human embryo development. The two types of domains, identified earlier as forests and prairies, become spatially segregated during e...

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Identifiers and source

Literature Corpus work: 82e616f6-08b7-500a-88da-36e9b220bbc8
DOI: 10.1101/521401

Open publication

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