Article
Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information.
Molecular and cellular biology - 1 Oct 2010
Zaidi Sayyed K, Young Daniel W, Montecino Martin, Lian Jane B, Stein Janet L, van Wijnen Andre J, Stein Gary S
Abstract excerpt
Epigenetic regulatory information must be retained during mammalian cell division to sustain phenotype-specific and physiologically responsive gene expression in the progeny cells. Histone modifications, DNA methylation, and RNA-mediated silencing are well-defined epigenetic mechanisms that control the cellular phenotype by regulating gene expression. Recent results suggest that the mitotic retention of nuclease...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
