Article

Maintenance DNA methylation is required for induced regulatory T cell reparative function following viral pneumonia

2025-03-01

Abstract excerpt

FOXP3+ natural regulatory T cells (nTregs) promote resolution of inflammation and repair of epithelial damage following viral pneumonia-induced lung injury, thus representing a cellular therapy for patients with acute respiratory distress syndrome (ARDS). Whether in vitro induced Tregs (iTregs), which can be rapidly generated in substantial numbers from conventional T cells, also promote lung recovery is unknown....

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Identifiers and source

Literature Corpus work: 824281d5-1cd0-5fd0-a6be-e0ff19dae198
DOI: 10.1101/2025.02.25.640199

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