Article
Influenza infection recruits distinct waves of regulatory T cells to the lung that limit lung resident IgA+ B cells
2022-09-19
Abstract excerpt
The role of regulatory T cells (Tregs) in limiting responses to pathogens in tissues remains poorly described. We used scRNA-Seq and a newly generated Foxp3 -lineage reporter line ( Foxp3-iDTR mice) to track Tregs in the lungs and peripheral blood following infection with influenza virus. Few Tregs of any type were found in the lung at steady-state. Following influenza infection Tregs expressing a strong interfe...
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Identifiers and source
- Literature Corpus work
- b6e60d01-15a0-58e3-826b-3b3a4eca8b2a
- DOI
- 10.1101/2022.09.19.508325
