Back to search

Article

Influenza infection recruits distinct waves of regulatory T cells to the lung that limit lung resident IgA+ B cells

2022-09-19

Abstract excerpt

The role of regulatory T cells (Tregs) in limiting responses to pathogens in tissues remains poorly described. We used scRNA-Seq and a newly generated Foxp3 -lineage reporter line ( Foxp3-iDTR mice) to track Tregs in the lungs and peripheral blood following infection with influenza virus. Few Tregs of any type were found in the lung at steady-state. Following influenza infection Tregs expressing a strong interfe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b6e60d01-15a0-58e3-826b-3b3a4eca8b2a
DOI
10.1101/2022.09.19.508325
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Influenza infection recruits distinct waves of regulatory T cells to the lung that limit lung resident IgA+ B cellsDOI 10.1101/2022.09.19.508325
Select a neighboring publication to make it the new centre.