Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Translational control in early development: CPEB, P-bodies and germinal granules

22 Jul 2008

Abstract excerpt

Selective protein synthesis in oocytes, eggs and early embryos of many organisms drives several critical aspects of early development, including meiotic maturation and entry into mitosis, establishment of embryonic axes and cell fate determination. mRNA-binding proteins which (usually) recognize 3'-UTR (untranslated region) elements in target mRNAs influence the recruitment of the small ribosomal subunit to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Syndromes and Imprinting
Share to Reproductive Biology and Fertility
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18631138
DOI: 10.1042/bst0360671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Translational control in early development: CPEB, P-bodies and germinal granulesPMID 18631138Read ↗

eIF4E1b is a non-canonical eIF4E required for maternal mRNA dormancySemantic proximity Read ↗

Two germ granule eIF4E isoforms reside in different mRNPs to hand off <i>C elegans</i> mRNAs from translational repression to activationSemantic proximity Read ↗

ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans.Semantic proximity Read ↗

Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.Semantic proximity Read ↗

eIF4E assembly into <i>C. elegans</i> germ granules is essential for its repressive functionSemantic proximity Read ↗

Protection of specific maternal messenger RNAs by the P body protein CGH-1 (Dhh1/RCK) during <i>Caenorhabditis elegans</i> oogenesisSemantic proximity Read ↗

Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap binding.Semantic proximity Read ↗

The active form of Xp54 RNA helicase in translational repression is an RNA-mediated oligomer.Semantic proximity Read ↗

Cap binding-independent recruitment of eIF4E to cytoplasmic foci.Semantic proximity Read ↗

The DAZL and PABP families: RNA-binding proteins with interrelated roles in translational control in oocytesSemantic proximity Read ↗

Coupled protein synthesis and ribosome-guided piRNA processing on mRNAsSemantic proximity Read ↗

Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.