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Two germ granule eIF4E isoforms reside in different mRNPs to hand off <i>C elegans</i> mRNAs from translational repression to activation

2024-05-26

Abstract excerpt

We studied the function of translation factor eIF4E isoforms in regulating mRNAs in germ cell granules/condensates. Translational control of mRNAs plays an essential role in germ cell gene regulation. Messenger ribonucleoprotein (mRNP) complexes assemble on mRNAs as they move from the nucleus into perinuclear germ granules to exert both positive and negative post-transcriptional regulation in the cytoplasm. In C....

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Identifiers and source

Literature Corpus work
73584e09-f055-50f3-b93c-aabc60360019
DOI
10.1101/2024.05.24.595216
Open publication

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Two germ granule eIF4E isoforms reside in different mRNPs to hand off <i>C elegans</i> mRNAs from translational repression to activationDOI 10.1101/2024.05.24.595216
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