Article

EFA6B regulates a stop signal for collective invasion in breast cancer

2020-03-20

Abstract excerpt

Cancer is initiated by somatic mutations in oncogenes or tumor suppressor genes, however additional mutations provide selective advantages to the tumor cells to resist treatment and develop metastases, therefore identification of secondary mutations is of paramount importance. EFA6B (Exchange Factor for ARF6, B) expression is reduced in breast cancer. To study the pro-tumoral impact of the loss of EFA6B we have in...

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Literature Corpus work: 81f3b10b-41fe-5659-8ab9-fe5ba9f44a10
DOI: 10.1101/2020.03.19.998575

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