Article

Extradomain-B Fibronectin is a molecular marker of invasive breast cancer cells

2019-08-22

Abstract excerpt

Breast tumor heterogeneity is a major impediment to oncotherapy. Tumor cells undergo rapid clonal evolution, thereby acquiring significant growth and invasive advantages. The absence of specific markers of these high-risk tumors precludes efficient therapeutic and diagnostic management of breast cancer. Given the critical function of tumor microenvironment in the oncogenic circuitry, we sought to determine the rol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c0f98402-75fc-552a-9932-13bdb175214e
DOI: 10.1101/743500

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Extradomain-B Fibronectin is a molecular marker of invasive breast cancer cellsDOI 10.1101/743500Read

Overexpression of Extradomain-B Fibronectin is Associated with Invasion of Breast Cancer CellsSemantic proximity Read

Breast cancer cells interact with tumor-derived extracellular matrix in a molecular subtype-specific mannerSemantic proximity Read

Shaping Up the Tumor Microenvironment With Cellular FibronectinSemantic proximity Read

Exploring the mechanism of fibronectin extra domain B in the tumor microenvironment and implications for targeted immunotherapy and diagnostics (Review)Semantic proximity Read

Integrins Alpha-2 and Beta-1 expression increases through Multiple Generations of the EDW01 Patient-Derived Xenograft Model of Breast Cancer - insight into their role in Epithelial Mesenchymal Transition in vivo gained from an in vitro model systemSemantic proximity Read

Molecular heterogeneity in breast carcinoma cells with increased invasive capacities.Semantic proximity Read

RNA-Seq Analysis of Extradomain A and Extradomain B Fibronectin as Extracellular Matrix Markers for CancerSemantic proximity Read

Fibronectin, DHPS and SLC3A2 Signaling Cooperate to Control Tumor Spheroid Growth, Subcellular eIF5A1/2 Distribution and CDK4/6 Inhibitor ResistanceSemantic proximity Read

Tumor-Resident Stromal Cells Promote Breast Cancer Invasion through Regulation of the Basal Phenotype.Semantic proximity Read

Tumor-extracellular matrix interactions: Identification of tools associated with breast cancer progressionSemantic proximity Read

Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer.Semantic proximity Read

Tumor-Associated EDA-FN-Enriched Matrix Instructs Macrophage BehaviorSemantic proximity Read