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Article

Analysis of multiple related phenotypes in genome-wide association studies.

Journal of bioinformatics and computational biology - 1 Oct 2016

Oh Sohee, Huh Iksoo, Lee Seung Yeoun, Park Taesung

Abstract excerpt

Most genome-wide association studies (GWAS) have been conducted by focusing on one phenotype of interest for identifying genetic variants associated with common complex phenotypes. However, despite many successful results from GWAS, only a small number of genetic variants tend to be identified and replicated given a very stringent genome-wide significance criterion, and explain only a small fraction of phenotype...

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PMID: 27774872
DOI: 10.1142/S0219720016440054

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